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The siRNA-mediated downregulation of PD-1 alone or simultaneously with CTLA-4 shows enhanced in-vitro CAR-T cell functionality for further clinical development towards the potential use in immunotherapy of melanoma.

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Description scientific article published on 28 April 2018
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author: Ugur Uslu  Beatrice Schuler-Thurner 

Publication date July 1, 2018
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