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Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development.

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Description scientific article published on 11 September 2003
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author: Roseline d'Oiron  Claude Negrier  Jean-Claude Bordet  Valerie Chamouard 

Publication date September 11, 2003
Language English
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