Pyrrolo[1,2-b][1,2,5]benzothiadiazepines (PBTDs) exert their anti-proliferative activity by interfering with Akt-mTOR signaling and bax:bcl-2 ratio modulation in cells from chronic myeloid leukemic patients.
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| Description | scientific article published on April 2010 |
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author: Sergio Amadori Elisabetta Abruzzese Romano Silvestri |
| Publication date | April 1, 2010 |
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