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Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer.

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Description scientific article published on 15 February 2011
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author: Nathanael Gray  David M. Sabatini 

Publication date February 15, 2011
Language English
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