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Cytochrome b5 increases cytochrome P450 3A4-mediated activation of anticancer drug ellipticine to 13-hydroxyellipticine whose covalent binding to DNA is elevated by sulfotransferases and N,O-acetyltransferases.

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Description scientific article published on 15 March 2012
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author: Radek Indra  Věra Černá  Michaela Moserová  Marie Stiborová  René Kizek  Václav Martínek 

Publication date March 15, 2012
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