Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells.
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| Description | scientific article published on 23 March 2015 |
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author: Alessandra Soriani Stefano Cascinu Laura Bonfili Matteo Mozzicafreddo Anna Maria Eleuteri Maria Beatrice Morelli Claudio Cardinali |
| Publication date | March 23, 2015 |
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