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The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA.

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Description scientific article published on November 2012
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author: Sina Mozaffari-Jovin  Henning Urlaub  Reinhard Georg Lührmann  Markus C Wahl  Cindy L Will 

Publication date November 1, 2012
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