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The central helices of ApoA-I can promote ATP-binding cassette transporter A1 (ABCA1)-mediated lipid efflux. Amino acid residues 220-231 of the wild-type ApoA-I are required for lipid efflux in vitro and high density lipoprotein formation in vivo.

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Description scientific article published on 17 December 2002
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author: Vassilis I Zannis  Irina Gorshkova 

Publication date December 17, 2002
Language English
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