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U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells.

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Description scientific article published on 14 May 2014
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author: Petr Pávek  Tomas Smutny  Zdeněk Dvořák 

Publication date May 14, 2014
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