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The constitutive androstane receptor activator 4-[(4R,6R)-4,6-diphenyl-1,3-dioxan-2-yl]-N,N-dimethylaniline inhibits the gluconeogenic genes PEPCK and G6Pase through the suppression of HNF4α and FOXO1 transcriptional activity.

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author: Vladimir O. Pustylnyak  Andrei Yarushkin 

Publication date April 1, 2013
Language English
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