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Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria.

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author: Tom Vanden Berghe  Sofie Claerhout  Peter Vandenabeele  Patrizia Agostinis 

Publication date January 1, 2010
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