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The anticancer activity of the substituted pyridone-annelated isoindigo (5'-Cl) involves G0/G1 cell cycle arrest and inactivation of CDKs in the promyelocytic leukemia cell line HL-60.

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author: Mustafa M El-Abadelah  Jalal A Zahra  Mohammad Azhar Aziz  Ayman M Saleh  Mutasem O. Taha  Ahmad Aljada 

Publication date March 27, 2015
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