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The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.

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Description scientific article published on 2 November 2015
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author: Paola Costanzo  Urban Gullberg 

Publication date November 2, 2015
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