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Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

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Description scientific article published on 15 February 2008
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author: Johan H. van Es  Ursula Zimber-Strobl  Freddy Radtke  Luca Pellegrinet  Tasuku Honjo  Lothar J Strobl 

Publication date February 15, 2008
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