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A novel tricyclic ligand-containing nonpeptidic HIV-1 protease inhibitor, GRL-0739, effectively inhibits the replication of multidrug-resistant HIV-1 variants and has a desirable central nervous system penetration property in vitro.

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Description scientific article
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author: Masayuki Amano  Prasanth R Nyalapatla 

Publication date February 17, 2015
Language English
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