Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).
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| Description | scientific article |
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author: Takumi Ito |
| Publication date | December 13, 2013 |
| Language | English |
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