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Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 [...]

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Description scientific article
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author: Carole A. Bewley  G. Marius Clore 

Publication date August 19, 2009
Language English
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