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The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.

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Description scientific article
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author: Michael Bubser  Craig W. Lindsley  Marianne Amalric  Colleen M. Niswender  P. Jeffrey Conn  Corey R. Hopkins  Carrie K Jones  Anna Louise Blobaum  Kimberly Italiano  Ryan R. Morrison  Darren W. Engers  Jacob Bode 

Publication date November 16, 2011
Language English
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