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Discovery of the first M5-selective and CNS penetrant negative allosteric modulator (NAM) of a muscarinic acetylcholine receptor: (S)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydro-1H-imidazo[2,1-a]isoindol-5(9bH)-one (ML375)

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Description scientific article
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author: Patrick R Gentry  Craig W. Lindsley  Colleen M. Niswender  P. Jeffrey Conn  Nathan R Kett  Joel Harper  Masaya Kokubo  Hyekyung P Cho 

Publication date November 27, 2013
Language English
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