MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.
scientific article
Author/s
author:
Robert F. H. Walter,
Saskia Ting,
Fabian D Mairinger
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