Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor
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| Description | scientific article |
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author: J.L. Henderson Yi Chen B.L. Kormos M.M. Hayward E. Needle P.R. Verhoest T.T. Wager C. Houle R.G. Kurumbail K.J. Coffman S.J. Steyn P. Galatsis W.D. Hirst J. Jasti G Stephen Noell Z. Berger |
| Publication date | January 8, 2015 |
| Language | English |
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