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Spirocyclic Sulfamides as β-Secretase 1 (BACE-1) Inhibitors for the Treatment of Alzheimer’s Disease: Utilization of Structure Based Drug Design, WaterMap, and CNS Penetration Studies To Identify Centrally Efficacious Inhibitors

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Description scientific article published on October 8, 2012
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author: Felix Vajdos 

Publication date November 8, 2012
Language English
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https://pubs.acs.org/doi/pdf/10.1021/jm3009426

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