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The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer

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Description scientific article
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author: Wendy K. Alderton  Paul A Clarke  Marketa J Zvelebil  Laurent Salphati  Paul Workman 

Publication date September 25, 2008
Language English
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