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The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

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Description scientific article
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author: Cyrus V Hedvat  Patrick S. Ward  Craig B. Thompson  David R Wise  Omar Abdel-Wahab  Justin R. Cross 

Publication date February 18, 2010
Language English
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